Warriors defensive linkman Marvelous Nakamba has earned his first XI appearance in the league at Aston Villa this season after being named in the starting line-up against Burnley.
The Zimbabwean midfielder was used from the bench as a late second-half substitute in all the previous games of the 2020/21 campaign.
The opportunity to start follows the suspension of Douglas Luiz, who was sent off in the 1-0 win over Wolves last week.
The other option in that position, Ross Barkley, is not available due to an injury.
Kick-off is at 8 pm and the match will be live on SuperSport TV’s Premier League channel.